This editorial serves as the introduction to the American Academy of Orthotists and Prosthetists State-of-the-Science Conference Proceedings covering the subject of upper-limb prosthetic control strategies. The purpose of the introduction is to orient consumers of the Proceedings regarding the breadth of its contents. Specifically, the conference centered about a systematic literature review comparing benefits of myoelectric and body-powered upper-limb prosthetic control options. The introduction lists the various perspectives such as clinical, engineering, and end-users represented at the face-to-face conference. It then introduces larger topics discussed by the conference participants, such as the traditional manner in which upper-limb prosthetic control strategies are introduced as well as viewpoints regarding standard of care. (J Prosthet Orthot. 2017;29:P1–P3)